Blood profile and oxidative biomarkers in goats on cassava based diets containing varying levels of sodium humate
Timothy Tertsegha Ikyume, Samson Abuchi Eze, Abiola Famous Lateef, John Abah Anawo, Dondo Stephen Donkoh, Samson Ojila
Abstract: The detoxifying abilities of the humic acids and its antioxidant capacity have led to an increased
interest in its use as feed additive in livestock production. This research assessed the physiological
and antioxidant response of West African dwarf (WAD) goats to cassava peels based diets containing
different levels of sodium humate. The experimental design was a completely randomized design,
with four treatment diets containing sodium humate at 0, 5, 10 and 15 g/kg diet (Control, 5HNa,
10HNa and 15HNa). Twenty (20) WAD bucks were divided into four (4) groups of five (5) animals
and assigned to the four experimental diets. Data was collected on haematological parameters, serum
indices and oxidative stress biomarkers and statistically analyzed using the GLM of SPSS (version
23). Result revealed that sodium humate in cassava peels based diets of WAD goats did not affect (p
> 0.05) the haematological parameters measured. Total protein increased (p < 0.05) in cassava peels
based diet containing 5 g/kg diet (6.43 mg/dL) of sodium humate compared to the other groups (5.50,
5.75 and 5.99 mg/dL for control, 10HNa and 15HNa groups respectively). Also, sodium humate in
cassava peels based diets reduce (p < 0.05) glucose level in the blood compared to the control. Serum
aluminum increased (p < 0.05) in 10HNa group (0.33 μgL-1) compared to the 5HNa group (0.30 μgL-1)
but not in the control and 15HNa groups (0.31 μgL-1, respectively). Albumin concentration increased
(p < 0.05) in all sodium humate groups (5.23, 5.50 and 5.48 mg/dL for %HNa, 10HNa, and 15HNa,
respectively) compared to the control (3.50 mg/dL). Uric acid increased (p < 0.05) with the increasing
amount of sodium humate in the cassava peels based diets. In conclusion, to address the concerns of
possible cyanide poisoning and mycotoxins in the mixed diets containing cassava peels, up to 15 g/kg
diet of sodium humate could be used as additive to improve the physiological and antioxidant capacity
of the animals.
interest in its use as feed additive in livestock production. This research assessed the physiological
and antioxidant response of West African dwarf (WAD) goats to cassava peels based diets containing
different levels of sodium humate. The experimental design was a completely randomized design,
with four treatment diets containing sodium humate at 0, 5, 10 and 15 g/kg diet (Control, 5HNa,
10HNa and 15HNa). Twenty (20) WAD bucks were divided into four (4) groups of five (5) animals
and assigned to the four experimental diets. Data was collected on haematological parameters, serum
indices and oxidative stress biomarkers and statistically analyzed using the GLM of SPSS (version
23). Result revealed that sodium humate in cassava peels based diets of WAD goats did not affect (p
> 0.05) the haematological parameters measured. Total protein increased (p < 0.05) in cassava peels
based diet containing 5 g/kg diet (6.43 mg/dL) of sodium humate compared to the other groups (5.50,
5.75 and 5.99 mg/dL for control, 10HNa and 15HNa groups respectively). Also, sodium humate in
cassava peels based diets reduce (p < 0.05) glucose level in the blood compared to the control. Serum
aluminum increased (p < 0.05) in 10HNa group (0.33 μgL-1) compared to the 5HNa group (0.30 μgL-1)
but not in the control and 15HNa groups (0.31 μgL-1, respectively). Albumin concentration increased
(p < 0.05) in all sodium humate groups (5.23, 5.50 and 5.48 mg/dL for %HNa, 10HNa, and 15HNa,
respectively) compared to the control (3.50 mg/dL). Uric acid increased (p < 0.05) with the increasing
amount of sodium humate in the cassava peels based diets. In conclusion, to address the concerns of
possible cyanide poisoning and mycotoxins in the mixed diets containing cassava peels, up to 15 g/kg
diet of sodium humate could be used as additive to improve the physiological and antioxidant capacity
of the animals.
Keywords: antioxidant; Blood profile; Cassava peels; sodium humate; WAD goats
Date published: 2022-08-29
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