CLINICAL TRIAL OF FLORFENIL 10 SOLUTION FOR PIGS AFFECTED BY COINFECTION OF PORCINE CIRCOVIRUS DISEASE AND COLIBACILOSIS

Simeon Yordanov, Albena Dimitrova, Krasimira Petkova, Christina Taseva

Abstract: In pig farm with proven associated infection of circovirus disease (PCVD) and colibacillosis is tested therapeutic effectiveness of Florfenil 10% – solution (Sudahim) in pigs 30 days of age and average bodyweight 10 kg. The pigs of the test group (n – 10) are treated individual per os with Florfenil 10% – solution, at a dose of 20 mg Florfenicol per kg b. w./day, 5 consecutive days, and the pigs of the control group not treated with anything. The animals are housed under the same technology parameters. Five days prior to treatment and 7 days after the last treatment with Florfenil 10%, of pigs in the two groups was recorded liveweight and are taken rectal swab-samples for bacteriological examination. By the end of the test period the animals in the experimental group remained in good physical and clinical condition. Not registered gastroenteritis and other bacterial diseases. In two pigs (20%) are observed respiratory difficulties which the end of the experiment were reserved only in one of them. In the control group were registered signs of PCVD and colibacillosis caused the death of one pig (10%) and less by 0.581 kg received from pig growth. At the end of the experiment the rectal samples which are positive for E. coli are 40% in the experimental group, and 80% in the control group. Isolated strains are 52.6% sensitive, 31.6% – intermediate, and 15.8% – resistant to florfenicol.

Keywords: clinical testing; colibacillosis; florfenil; pigs; therapeutic efficacy

Date published: 2017-11-10