ДНК МАРКЕРИ И ТЯХНОТО ПРИЛОЖЕНИЕ В ЖИВОТНОВЪДСТВОТО

ДЕЯНА ХРИСТОВА, ЦАНКО ЯБЛАНСКИ, ЕЛЕНА ТОДОРОВСКА

Abstract: The remarkable achievements in molecular biology and biotechnology as well as the development of high-throughput platforms for sequencing of human, other mammals and some livestock’s genomes during the last 10 years have allowed the discovery of large number DNA polymorphisms that can be used as markers for studying the genetic base of the diversity at phenotype level. A special attention is given to the basic features of widely used DNA markers and their application in molecular genetic studies of economically important livestock such as genotype identification, assessment of genetic diversity and genetic structure of populations, pedigree determination, inbreeding, genetic drift, mapping of QTLs for traits of economic importance, etc. Herein is also discussed the possible application of DNA markers for characterization the genetic resources of the populations as a basis for the development and optimization of strategies for their conservation and rational use in breeding programs at both worldwide and national scale.

Keywords: развъдни стратегии; ДНК маркери; добитък; полиморфизъм

Date published: 2023-03-09