THE GENETIC SCREENING FOR BLAD, DUMPS, BC IN UKRAINIAN DAIRY CATTLE

OLGA BIRUKOVA, MARIA DOBRIANSKAYA, NATALIA MAKOVSKAYA,, OLEXANDER KOSTENKO, CYRIL KOPYLOV, SERGIY RUBAN, OLENA FEDOTA

Abstract: Bovine leukocyte adhesion deficiency (BLAD), deficiency of uridine monophosphate synthase (DUMPS), bovine citrullinaemia (BC) are hereditary autosomal recessive disorders of cattle. The goal of this investigation is to estimate the frequence of BLAD, DUMPS, BC alleles in Ukrainian dairy cattle. Twenty two Holstein, Red-and-White, Black-and-White dairy breed’s bulls from the different provinces of Ukraine were sampled after genealogical analysis of 600 buls. Genotyping for ITGB2, uridine monophosphate synthase (UMPS), argininosuccinate synthase (ASS) genes was done using PCR-RFLP method. One BLAD allele carrier was found among the 22 bulls. While carriers of DUMPS and BC alleles were not detected. Screening for such recessive disorders has significant economic impact on dairy cattle breeding in Ukraine and worldwide.

Keywords: BC; BLAD; bulls; dairy cattle; DUMPS; genealogical analysis

Date published: 2023-01-31